Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.63 |
| ▸ | IGF1R | P08069 | 3/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14035242 | 1.00 | GAA (0.65) | GAAKMT2AMEN1KDM4EOPRM1 | |
| SCHEMBL2797036 | 1.00 | GAA (0.65) | GAAKMT2AMEN1KDM4EOPRM1 | |
| SCHEMBL24672687 | 0.98 | GAA (0.63) | GAAKMT2AMEN1KDM4EOPRM1 | |
| Hydrochloric Acid SCHEMBL3844155 | 0.98 | GAA (0.63) | GAAKMT2AMEN1KDM4EOPRM1 | |
| Hydrochloric Acid SCHEMBL4463433 | 0.98 | GAA (0.63) | GAAKMT2AMEN1KDM4EOPRM1 | |
| Hydrochloric Acid SCHEMBL4463437 | 0.98 | GAA (0.63) | GAAKMT2AMEN1KDM4EOPRM1 | |
| SCHEMBL31341398 | 0.91 | KMT2A (0.61) | GAAKMT2AMEN1KDM4EOPRM1 | |
| SCHEMBL2796836 | 0.87 | GAA (0.82) | GAAKMT2AMEN1KDM4EOPRM1 | |
| SCHEMBL10746494 | 0.87 | GAA (0.82) | GAAKMT2AMEN1KDM4EOPRM1 | |
| SCHEMBL28761705 | 0.84 | GRIN2B (0.48) | GAAKMT2AMEN1KDM4EOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134036-A1 | ALPHA-SUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-α]PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |