Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4095744 | 1.00 | MEN1 (0.59) | MEN1KMT2AKCNH2KCNA5SLC6A4 | |
| SCHEMBL14035305 | 1.00 | MEN1 (0.59) | MEN1KMT2AKCNH2KCNA5SLC6A4 | |
| Hydrochloric Acid SCHEMBL23211984 | 0.98 | MEN1 (0.58) | MEN1KMT2AKCNH2KCNA5SLC6A4 | |
| SCHEMBL30330107 | 0.84 | SLC6A2 (0.48) | MEN1KMT2AKCNH2KCNA5SLC6A4 | |
| SCHEMBL16121132 | 0.83 | CYP2D6 (0.41) | MEN1KMT2AKCNH2KCNA5SLC6A4 | |
| SCHEMBL31010334 | 0.81 | KCNA5 (0.57) | MEN1KMT2AKCNH2KCNA5CYP2D6 | |
| Hydrochloric Acid SCHEMBL7405456 | 0.80 | KCNA5 (0.55) | MEN1KMT2AKCNH2KCNA5CYP2D6 | |
| SCHEMBL6926672 | 0.79 | CYP2D6 (0.59) | MEN1KMT2AKCNH2KCNA5SLC6A4 | |
| SCHEMBL4094666 | 0.78 | HRH3 (0.42) | MEN1KMT2AKCNH2KCNA5SLC6A4 | |
| SCHEMBL4099833 | 0.78 | HRH3 (0.42) | MEN1KMT2AKCNH2KCNA5SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134036-A1 | ALPHA-SUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-α]PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |