Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.45 |
| ▸ | TACR3 | P29371 | 6/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375146 | 0.92 | KDM4E (0.50) | KDM4ESMN1; SMN2ALDH1A1UCHL1TACR3 | |
| SCHEMBL6011641 | 0.92 | KDM4E (0.50) | KDM4ESMN1; SMN2ALDH1A1UCHL1TACR3 | |
| SCHEMBL2617528 | 0.92 | KDM4E (0.50) | KDM4ESMN1; SMN2ALDH1A1UCHL1TACR3 | |
| SCHEMBL8261052 | 0.92 | KDM4E (0.50) | KDM4ESMN1; SMN2ALDH1A1UCHL1TACR3 | |
| SCHEMBL8275065 | 0.91 | KDM4E (0.48) | KDM4ESMN1; SMN2ALDH1A1UCHL1TACR3 | |
| SCHEMBL9971085 | 0.91 | KDM4E (0.48) | KDM4ESMN1; SMN2ALDH1A1UCHL1TACR3 | |
| SCHEMBL13123350 | 0.91 | KDM4E (0.48) | KDM4ESMN1; SMN2ALDH1A1UCHL1TACR3 | |
| SCHEMBL12744677 | 0.89 | KDM4E (0.47) | KDM4ESMN1; SMN2ALDH1A1UCHL1TACR3 | |
| SCHEMBL16938888 | 0.89 | KDM4E (0.47) | KDM4ESMN1; SMN2ALDH1A1UCHL1TACR3 | |
| SCHEMBL13340509 | 0.88 | KDM4E (0.46) | KDM4ESMN1; SMN2ALDH1A1UCHL1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505945-B1 | SUBSTITUTED CYCLOALKYL P1' HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-11-05 | — | — | EP | disclosed |