Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14009161 | 0.89 | EPHX1 (0.33) | EPHX1HPSE | |
| SCHEMBL14655843 | 0.88 | PRMT1 (0.40) | EPHX2EPHX1HPSE | |
| SCHEMBL5054500 | 0.86 | EPHX2 (0.38) | EPHX2EPHX1HPSEHDAC8 | |
| SCHEMBL440073 | 0.76 | EPHX2 (0.38) | EPHX2LMNA | |
| SCHEMBL436883 | 0.75 | TSHR (0.38) | EPHX2LMNA | |
| SCHEMBL21189870 | 0.74 | GAA (0.43) | HDAC8 | |
| SCHEMBL25516343 | 0.73 | HPSE (0.31) | HPSE | |
| SCHEMBL25409984 | 0.73 | TSHR (0.52) | EPHX2LMNAHDAC8 | |
| SCHEMBL13446630 | 0.73 | TSHR (0.52) | EPHX2LMNAHDAC8 | |
| SCHEMBL13651616 | 0.73 | TSHR (0.52) | EPHX2LMNAHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9671396-B2 | Solid substrate comprising array of dendrons and methods for using the same | PARK JOON WON (KR) | 2017-06-06 | — | — | US | disclosed |
| US-9389227-B2 | Solid substrate comprising array of dendrons and methods for using the same | POSCO (KR) | 2016-07-12 | — | — | US | disclosed |
| US-9201067-B2 | Size-controlled macromolecule | POSCO (KR) | 2015-12-01 | — | — | US | disclosed |
| US-9175335-B2 | Biomolecule interaction using atomic force microscope | POSCO (KR) | 2015-11-03 | — | — | US | disclosed |
| US-20140315319-A1 | BIOMOLECULE INTERACTION USING ATOMIC FORCE MICROSCOPE | POSCO (KR) | 2014-10-23 | — | — | US | disclosed |
| EP-1664341-B1 | SIZE-CONTROLLED MACROMOLECULE | POSCO (KR) | 2013-01-30 | — | — | EP | disclosed |
| US-20100093553-A1 | Solid Substrate Comprising Array of Dendrons and Methods for Using the Same | PARK JOON WON | 2010-04-15 | — | — | US | disclosed |
| US-20080274915-A1 | Solid Substrate Comprising Array of Dendrons and Methods for Using the Same | PARK JOON WON | 2008-11-06 | — | — | US | disclosed |
| US-20070128623-A1 | Cantilevers with fixed end and free end modified by dendron | POSTECH FOUNDATION (KR) | 2007-06-07 | — | — | US | disclosed |