Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 4/20 | 0.39 |
| ▸ | F3 | P13726 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | F11 | P03951 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5002743 | 0.89 | F7 (0.51) | KMT2AMEN1TDP1MAPTL3MBTL1 | |
| SCHEMBL14035953 | 0.87 | TDP1 (0.41) | KMT2AMEN1TDP1MAPTL3MBTL1 | |
| SCHEMBL4599433 | 0.79 | F10 (0.47) | KMT2AMEN1TDP1MAPTL3MBTL1 | |
| SCHEMBL14009202 | 0.76 | F7 (0.53) | KMT2AMEN1TDP1MAPTL3MBTL1 | |
| SCHEMBL14009133 | 0.72 | F7 (0.54) | KMT2AMEN1TDP1MAPTL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL5003012 | 0.72 | F7 (0.49) | KMT2AMEN1TDP1MAPTL3MBTL1 | |
| SCHEMBL8251269 | 0.71 | F7 (0.54) | KMT2AMEN1TDP1MAPTL3MBTL1 | |
| SCHEMBL14009147 | 0.70 | F7 (0.53) | KMT2AMEN1TDP1MAPTL3MBTL1 | |
| SCHEMBL14009175 | 0.70 | F7 (0.53) | KMT2AMEN1TDP1MAPTL3MBTL1 | |
| SCHEMBL4598702 | 0.70 | F7 (0.52) | KMT2AMEN1TDP1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456195-B2 | Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-25 | — | — | US | disclosed |