Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 19/20 | 0.60 |
| ▸ | RAMP1 | O60894 | 4/20 | 0.60 |
| ▸ | CALCA | P06881 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2165855 | 0.95 | CALCRL (0.64) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL14036125 | 0.95 | CALCRL (0.64) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL14016418 | 0.94 | CALCRL (0.65) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL14036241 | 0.93 | CALCRL (0.59) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL14016734 | 0.92 | CALCRL (0.69) | CALCRLRAMP1 | |
| SCHEMBL14036162 | 0.92 | CALCRL (0.61) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL14016978 | 0.92 | CALCRL (0.58) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL14036155 | 0.91 | CALCRL (0.60) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL2166209 | 0.90 | CALCRL (0.69) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL2166221 | 0.90 | CALCRL (0.69) | CALCRLRAMP1CALCACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992349-A1 | CGRP antagonists, their preparation and use as a medicament | Boehringer Ingelheim International GmbH (DE) | 2008-11-19 | — | — | EP | disclosed |