Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 6/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8291841 | 1.00 | SLC29A1 (0.54) | SLC29A1HPGDSLMNAGRIN2BKCNH2 | |
| SCHEMBL8291853 | 1.00 | SLC29A1 (0.54) | SLC29A1HPGDSLMNAGRIN2BKCNH2 | |
| SCHEMBL14010240 | 1.00 | SLC29A1 (0.54) | SLC29A1HPGDSLMNAGRIN2BKCNH2 | |
| SCHEMBL8291855 | 1.00 | SLC29A1 (0.54) | SLC29A1HPGDSLMNAGRIN2BKCNH2 | |
| SCHEMBL8291852 | 1.00 | SLC29A1 (0.54) | SLC29A1HPGDSLMNAGRIN2BKCNH2 | |
| SCHEMBL14010256 | 1.00 | SLC29A1 (0.54) | SLC29A1HPGDSLMNAGRIN2BKCNH2 | |
| SCHEMBL5007176 | 1.00 | SLC29A1 (0.54) | SLC29A1HPGDSLMNAGRIN2BKCNH2 | |
| SCHEMBL5006171 | 0.94 | SLC29A1 (0.56) | SLC29A1HPGDSLMNAGRIN2BKCNH2 | |
| SCHEMBL14010494 | 0.94 | SLC29A1 (0.56) | SLC29A1HPGDSLMNAGRIN2BKCNH2 | |
| SCHEMBL5006174 | 0.94 | SLC29A1 (0.56) | SLC29A1HPGDSLMNAGRIN2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452893-B2 | 4-cycloakylaminopyrazolo pyrimidine NMDA/NR2B antagonists | MERCK & CO., INC. (US) | 2008-11-18 | — | — | US | disclosed |