Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 19/20 | 0.77 |
| ▸ | RAMP1 | O60894 | 2/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CALCA | P06881 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12404676 | 1.00 | CALCRL (0.77) | CALCRLRAMP1CYP3A4CALCA | |
| SCHEMBL2177231 | 0.98 | CALCRL (0.78) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL2177241 | 0.98 | CALCRL (0.78) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14016946 | 0.96 | CALCRL (0.70) | CALCRLRAMP1CYP3A4CALCA | |
| SCHEMBL2166120 | 0.95 | CALCRL (0.73) | CALCRLRAMP1CALCA | |
| SCHEMBL2164781 | 0.93 | CALCRL (0.67) | CALCRLRAMP1CYP3A4CALCA | |
| SCHEMBL2164771 | 0.93 | CALCRL (0.67) | CALCRLRAMP1CYP3A4CALCA | |
| SCHEMBL14016606 | 0.93 | CALCRL (0.66) | CALCRLRAMP1CYP3A4CALCA | |
| SCHEMBL2167164 | 0.93 | CALCRL (0.80) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL2167158 | 0.93 | CALCRL (0.80) | CALCRLRAMP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992349-A1 | CGRP antagonists, their preparation and use as a medicament | Boehringer Ingelheim International GmbH (DE) | 2008-11-19 | — | — | EP | disclosed |