Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449374 | 0.92 | EGFR (0.83) | EGFR | |
| Hydrochloric Acid SCHEMBL4448536 | 0.91 | EGFR (0.82) | EGFR | |
| SCHEMBL4443010 | 0.86 | EGFR (0.89) | EGFR | |
| SCHEMBL4447017 | 0.85 | EGFR (0.74) | EGFR | |
| SCHEMBL13607128 | 0.85 | EGFR (0.72) | EGFR | |
| SCHEMBL4448863 | 0.84 | EGFR (0.85) | EGFR | |
| SCHEMBL6010138 | 0.84 | EGFR (0.72) | EGFR | |
| SCHEMBL14364773 | 0.84 | EGFR (0.70) | EGFR | |
| Hydrochloric Acid SCHEMBL4445060 | 0.84 | EGFR (0.84) | EGFR | |
| SCHEMBL4441299 | 0.83 | EGFR (0.83) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713781-B1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-11-05 | — | — | EP | disclosed |