Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126001 | 0.78 | CYP4F2 (0.42) | CYP4F2CYP4A11ABCB11CYP1A2CYP3A4 | |
| SCHEMBL28724880 | 0.73 | CYP4F2 (0.38) | CYP4F2CYP4A11MMP8MAPT | |
| SCHEMBL1245761 | 0.66 | CYP4F2 (0.50) | CYP4F2CYP4A11ABCB11CYP1A2CYP3A4 | |
| SCHEMBL14218515 | 0.66 | CYP4F2 (0.50) | CYP4F2CYP4A11ABCB11CYP1A2CYP3A4 | |
| SCHEMBL8354123 | 0.66 | GAA (0.48) | CYP1A2TSHRPOLBALDH1A1 | |
| SCHEMBL8888149 | 0.66 | CYP4F2 (0.50) | CYP4F2CYP4A11ABCB11CYP1A2CYP3A4 | |
| SCHEMBL1829725 | 0.66 | CYP4F2 (0.50) | CYP4F2CYP4A11TSHRPIN1ALDH1A1 | |
| SCHEMBL3468249 | 0.66 | CYP4F2 (0.44) | CYP4F2CYP4A11ABCB11CYP1A2CYP3A4 | |
| SCHEMBL10596544 | 0.65 | TSHR (0.56) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL12121808 | 0.64 | CYP4F2 (0.48) | CYP4F2CYP4A11ABCB11CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137609-A1 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | AMIRA PHARMACEUTICALS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |