⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21417982 | 0.83 | MGMT (0.30) | — | |
| SCHEMBL14901052 | 0.81 | — | — | |
| SCHEMBL14037077 | 0.81 | — | — | |
| SCHEMBL13555278 | 0.79 | — | — | |
| SCHEMBL14361118 | 0.76 | FFAR1 (0.31) | — | |
| SCHEMBL13508063 | 0.76 | — | — | |
| SCHEMBL13589430 | 0.76 | — | — | |
| SCHEMBL13558769 | 0.74 | — | — | |
| SCHEMBL14882672 | 0.74 | — | — | |
| SCHEMBL16380373 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080274173-A1 | Copolymer of crosslinkable or crosslinked poly(amino acid block), and a hydrophobic D,L-mixed poly(amino acid) block; an inner core, crosslinked outer core, a hydrophilic shell; improved in vivo circulation time; drug delivery | INTEZYNE TECHNOLOGIES, INC. (US) | 2008-11-06 | — | — | US | disclosed |