Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.38 |
| ▸ | ATP4A | P20648 | 1/20 | 0.36 |
| ▸ | ATP4B | P51164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21523873 | 0.91 | STAT3 (0.53) | STAT3STAT1RAB9AHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27856204 | 0.88 | STAT3 (0.50) | STAT3STAT1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL585094 | 0.87 | STAT3 (0.48) | STAT3STAT1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL585086 | 0.84 | STAT3 (0.55) | STAT3STAT1ATP4AATP4BTERT | |
| SCHEMBL584752 | 0.84 | STAT3 (0.50) | STAT3STAT1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL12230354 | 0.84 | STAT3 (0.46) | STAT3STAT1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL15673545 | 0.84 | STAT3 (0.46) | STAT3STAT1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL17722680 | 0.84 | STAT3 (0.46) | STAT3STAT1RAB9AHPGDSMN1; SMN2 | |
| Exeporfinium SCHEMBL585997 | 0.84 | STAT3 (0.52) | STAT3STAT1RAB9AHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL584371 | 0.83 | STAT3 (0.49) | STAT3STAT1RAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080281091-A1 | Process for the Preparation of Porphyrin Derivatives as Antimicrobial Agents by Photodynamic Therapy (Pdt) | BRUNDISH DEREK | 2008-11-13 | — | — | US | disclosed |