Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.42 |
| ▸ | TUBB | P07437 | 7/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270233 | 0.88 | NR1H4 (0.54) | NR1H4KMT2AMAPTNPC1RAB9A | |
| SCHEMBL3138277 | 0.87 | NR1H4 (0.58) | NR1H4KMT2AMAPTNPC1RAB9A | |
| SCHEMBL14013667 | 0.86 | NR1H4 (0.53) | NR1H4KMT2AMAPTNPC1RAB9A | |
| SCHEMBL3141244 | 0.83 | NR1H4 (0.47) | NR1H4KMT2AMAPTNPC1RAB9A | |
| SCHEMBL3127787 | 0.81 | NR1H4 (0.51) | NR1H4KMT2AMAPTNPC1RAB9A | |
| SCHEMBL3136921 | 0.81 | NR1H4 (0.55) | NR1H4KMT2AMAPTNPC1RAB9A | |
| SCHEMBL13270529 | 0.80 | NR1H4 (0.53) | NR1H4KMT2AMAPTNPC1RAB9A | |
| SCHEMBL3137512 | 0.77 | NR1H4 (0.42) | NR1H4KMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL3135730 | 0.76 | MAPT (0.46) | NR1H4MAPTSMN1; SMN2ALDH1A1TUBB4A | |
| SCHEMBL9058215 | 0.75 | KMT2A (0.70) | NR1H4KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456214-B2 | Cancer; for selectively destroying tumor vasculature; inhibit tubulin polymerization; selectively reducing blood flow to at least a portion of a neoplastic region; 3-(3',4',5'-Trimethoxybenzoyl)-6-hydroxy-7-methoxy-2H-chromene | BAYLOR UNIVERSITY (US) | 2008-11-25 | — | — | US | disclosed |