Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14038802 | 0.89 | PTGER1 (0.53) | CYP2C9PTGER1CNR1 | |
| SCHEMBL5096018 | 0.88 | PTGER1 (0.54) | NPC1CYP1A2CYP2C9RAB9ACYP2C19 | |
| SCHEMBL14029163 | 0.80 | PTGER1 (0.60) | NPC1CYP2C9RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14028965 | 0.80 | PTGER1 (0.60) | NPC1CYP2C9RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14028923 | 0.79 | PTGER1 (0.47) | NPC1CYP1A2CYP2C9RAB9ACYP2C19 | |
| SCHEMBL5109183 | 0.77 | PTGER1 (0.49) | CYP2C9HPGDPOLBPTGER1 | |
| SCHEMBL14028869 | 0.75 | PTGER1 (0.59) | NPC1CYP1A2CYP2C9RAB9ACYP2C19 | |
| SCHEMBL14039003 | 0.74 | CYP2C9 (0.46) | NPC1CYP1A2CYP2C9RAB9ACYP2C19 | |
| SCHEMBL5157932 | 0.74 | PTGER1 (0.69) | CYP2C9PTGER1 | |
| SCHEMBL5096241 | 0.74 | PTGER1 (0.54) | CYP2C9PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446222-B2 | Phenyl compounds | GLAXO GROUP LIMITED (GB) | 2008-11-04 | — | — | US | disclosed |