Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12393410 | 1.00 | TMPRSS2 (0.36) | TMPRSS2ADORA2A | |
| SCHEMBL10148586 | 0.89 | TMPRSS2 (0.35) | TMPRSS2 | |
| SCHEMBL12397055 | 0.89 | TMPRSS2 (0.35) | TMPRSS2 | |
| SCHEMBL12393401 | 0.88 | TMPRSS2 (0.36) | TMPRSS2ADORA2A | |
| SCHEMBL16519851 | 0.87 | ADORA2A (0.38) | TMPRSS2ADORA2A | |
| SCHEMBL12243240 | 0.87 | ADORA2A (0.38) | TMPRSS2ADORA2A | |
| SCHEMBL12393413 | 0.84 | TMPRSS2 (0.34) | TMPRSS2 | |
| SCHEMBL12393415 | 0.84 | TMPRSS2 (0.35) | TMPRSS2 | |
| SCHEMBL12393404 | 0.84 | TMPRSS2 (0.41) | TMPRSS2 | |
| SCHEMBL12393417 | 0.81 | ADORA2A (0.30) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318682-B2 | 1′substituted carba-nucleoside analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2012-11-27 | — | — | US | disclosed |