Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.34 |
| ▸ | CDC25B | P30305 | 6/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | GJB2 | P29033 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12393257 | 0.90 | PDE2A (0.37) | PDE2AHTR1AHSPA5PTPN1CDC25B | |
| SCHEMBL18636443 | 0.90 | PDE2A (0.37) | PDE2AHTR1AHSPA5PTPN1CDC25B | |
| SCHEMBL27086454 | 0.89 | PDE2A (0.37) | PDE2AHTR1AHSPA5PTPN1CDC25B | |
| SCHEMBL12243141 | 0.89 | PDE2A (0.37) | PDE2AHTR1AHSPA5PTPN1CDC25B | |
| SCHEMBL31063739 | 0.89 | PDE2A (0.37) | PDE2AHTR1AHSPA5PTPN1CDC25B | |
| SCHEMBL12393373 | 0.89 | PDE2A (0.37) | PDE2AHTR1AHSPA5PTPN1CDC25B | |
| SCHEMBL23685928 | 0.87 | PDE2A (0.36) | PDE2AHTR1AHSPA5PTPN1CDC25B | |
| SCHEMBL12393377 | 0.86 | PTPN1 (0.36) | PDE2AHTR1AHSPA5PTPN1CDC25B | |
| SCHEMBL25826686 | 0.86 | PDE2A (0.36) | PDE2AHTR1AHSPA5PTPN1CDC25B | |
| SCHEMBL12393251 | 0.86 | HSPA5 (0.37) | PDE2AHTR1AHSPA5PTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318682-B2 | 1′substituted carba-nucleoside analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2012-11-27 | — | — | US | disclosed |