Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.39 |
| ▸ | SARS1 | P49591 | 1/20 | 0.39 |
| ▸ | IARS1 | P41252 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.36 |
| ▸ | CDK2 | P24941 | 4/20 | 0.35 |
| ▸ | CDK1 | P06493 | 3/20 | 0.35 |
| ▸ | MARS1 | P56192 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374009 | 0.83 | SARS1 (0.40) | LARS1SARS1IARS1ADORA3MARS1 | |
| SCHEMBL14393325 | 0.83 | SARS1 (0.40) | LARS1SARS1IARS1ADORA3MARS1 | |
| SCHEMBL12374825 | 0.71 | ADORA2A (0.51) | IARS1ADORA3ADORA1ADORA2A | |
| SCHEMBL12009914 | 0.71 | ADORA2A (0.36) | ADORA3ADORA1ADORA2A | |
| SCHEMBL12009920 | 0.71 | ADORA2A (0.35) | ADORA2A | |
| SCHEMBL12374999 | 0.71 | ADORA2A (0.59) | IARS1ADORA3ADORA1ADORA2A | |
| SCHEMBL12009925 | 0.70 | ADORA2A (0.35) | ADORA2A | |
| SCHEMBL14393328 | 0.69 | MEN1 (0.40) | LARS1SARS1IARS1ADORA3CDK2 | |
| SCHEMBL3478702 | 0.69 | MEN1 (0.40) | LARS1SARS1IARS1ADORA3CDK2 | |
| SCHEMBL12374837 | 0.69 | MEN1 (0.33) | ADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130520-A1 | THERAPEUTIC AGENT FOR GLAUCOMA CONTAINING ADENOSINE DERIVATIVE AS ACTIVE INGREDIENT | SANTEN PHARMACEUTICAL CO., LTD (JP) | 2008-10-30 | — | — | WO | disclosed |