Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | MMP12 | P39900 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18174891 | 0.82 | NPC1 (0.42) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL24906570 | 0.71 | PTPN1 (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1HTT | |
| SCHEMBL14040054 | 0.70 | NPC1 (0.32) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14040032 | 0.70 | TNKS (0.35) | — | |
| SCHEMBL14040108 | 0.69 | CNR1 (0.33) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12386886 | 0.69 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL21237911 | 0.69 | AHR (0.47) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9963713 | 0.69 | AHR (0.47) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8610438 | 0.65 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25789591 | 0.65 | NPC1 (0.45) | SMN1; SMN2NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357436-B1 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KK (JP) | 2008-10-22 | — | — | EP | disclosed |