Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.88 |
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzonitrile SCHEMBL8713536 | 0.94 | TSHR (0.88) | TSHRMAOBMAOAAPPALDH1A1 | |
| Benzonitrile SCHEMBL1404152 | 0.94 | — | — | |
| Benzonitrile SCHEMBL28431334 | 0.94 | TSHR (0.88) | TSHRMAOBMAOAAPPALDH1A1 | |
| Benzonitrile SCHEMBL11044747 | 0.94 | — | — | |
| Benzonitrile SCHEMBL30929383 | 0.94 | TSHR (1.00) | TSHRMAOBMAOAAPPALDH1A1 | |
| Benzonitrile SCHEMBL27793280 | 0.94 | TSHR (1.00) | TSHRMAOBMAOAAPPALDH1A1 | |
| Benzonitrile SCHEMBL21752925 | 0.94 | — | — | |
| Benzonitrile SCHEMBL6640 | 0.94 | — | — | |
| Benzonitrile SCHEMBL9464940 | 0.94 | TSHR (1.00) | TSHRMAOBMAOAAPPALDH1A1 | |
| Benzonitrile SCHEMBL27363057 | 0.94 | TSHR (1.00) | TSHRMAOBMAOAAPPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230138553-A1 | A Process for the Preparation of Methylene Blue | DISHMAN CARBOGEN AMCIS LTD. (IN) | 2023-05-04 | — | — | US | disclosed |
| EP-4110735-A1 | A PROCESS FOR THE PREPARATION OF METHYLENE BLUE | Dishman Carbogen Amcis Ltd. (IN) | 2023-01-04 | — | — | EP | disclosed |
| CN-113105573-A | Cis-1, 4-polydienes having improved cold flow resistance | 株式会社普利司通 | 2021-07-13 | — | — | CN | disclosed |
| CN-107428871-B | Cis-1, 4-polydienes having improved cold flow resistance | 株式会社普利司通 | 2021-03-30 | — | — | CN | disclosed |
| US-10316121-B2 | Cis-1,4-polydienes with improved cold flow resistance | BRIDGESTONE CORPORATION (JP) | 2019-06-11 | — | — | US | disclosed |
| EP-3250617-B1 | CIS-1,4-POLYDIENES WITH IMPROVED COLD FLOW RESISTANCE | BRIDGESTONE CORP (JP) | 2019-01-02 | — | — | EP | disclosed |
| US-20180009919-A1 | Cis-1,4-Polydienes With Improved Cold Flow Resistance | BRIDGESTONE CORPORATION (JP) | 2018-01-11 | — | — | US | disclosed |
| EP-3250617-A1 | CIS-1,4-POLYDIENES WITH IMPROVED COLD FLOW RESISTANCE | Bridgestone Corporation (JP) | 2017-12-06 | — | — | EP | disclosed |
| CN-107428871-A | Cis-1, 4-polydienes having improved cold flow resistance | 株式会社普利司通 | 2017-12-01 | — | — | CN | disclosed |
| WO-2016123370-A1 | CIS-1,4-POLYDIENES WITH IMPROVED COLD FLOW RESISTANCE | BRIDGESTONE CORPORATION (JP) | 2016-08-04 | — | — | WO | disclosed |
| US-5283294-A | Crystalline polymer in rubber elastomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-02-01 | — | — | US | disclosed |
| EP-0489216-A1 | High modulus rubber compositions | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-06-10 | — | — | EP | disclosed |
| US-5100982-A | Halogenated Phenol | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-03-31 | — | — | US | disclosed |
| EP-0236253-B1 | PROCESS FOR BULK POLYMERIZING BUTADIENE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-12-18 | — | — | EP | disclosed |
| US-5049620-A | High modulus rubber composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-09-17 | — | — | US | disclosed |
| EP-0434596-A2 | High modulus rubber composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0336874-A1 | Inverse phase polymerization | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-10-11 | — | — | EP | disclosed |
| EP-0236253-A1 | Process for bulk polymerizing butadiene | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-09-09 | — | — | EP | disclosed |
| US-4383097-A | USING NONCONJUGATED DIOLEFINS HAVING TRANS CONFIGURATION AND A CATALYST OF AN ORGANO ALUMINUM-NICKEL-FLUORINE COMPLEY | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-05-10 | — | — | US | disclosed |
| US-3985677-A | POLYMERIZATION OF BUTADIENE ANDOR BUTADIENE WITH DIOLEFINS WITH HIGH CIS-1,4 ADDITION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138553-A1 | A Process for the Preparation of Methylene Blue | B2M, PURB, POLM | TSHR 2167/4885MAOB 45/4885MAOA 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.