Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.56 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | FADS1 | O60427 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | PAK4 | O96013 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996140 | 0.88 | TTBK1 (0.56) | TTBK1TTBK2EGFRCNR2CNR1 | |
| SCHEMBL3992608 | 0.81 | TTBK1 (0.53) | TTBK1TTBK2EGFRCNR2CNR1 | |
| SCHEMBL3993488 | 0.80 | MAPT (0.55) | TTBK1TTBK2CNR2CNR1SYK | |
| SCHEMBL13692196 | 0.78 | CNR2 (0.68) | TTBK1TTBK2CNR2CNR1MAPT | |
| Formic Acid SCHEMBL3990258 | 0.75 | CNR2 (0.64) | TTBK1TTBK2CNR2CNR1MAPT | |
| SCHEMBL14040912 | 0.74 | CNR2 (0.53) | TTBK1TTBK2CNR2CNR1CYP1A2 | |
| SCHEMBL4738813 | 0.72 | TTBK1 (1.00) | TTBK1TTBK2EGFRFADS1LCK | |
| SCHEMBL3989021 | 0.72 | CNR2 (0.60) | TTBK1TTBK2CNR2CNR1MAPT | |
| SCHEMBL12501075 | 0.72 | CYP1A2 (0.68) | EGFRFADS1CNR2CNR1LCK | |
| SCHEMBL3990560 | 0.71 | CNR2 (0.70) | TTBK1TTBK2CNR2CNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753764-B1 | PYRROLOPYRIDINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2008-10-29 | — | — | EP | disclosed |