Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 19/20 | 0.72 |
| ▸ | CCND1 | P24385 | 17/20 | 0.72 |
| ▸ | CCND2 | P30279 | 16/20 | 0.72 |
| ▸ | CCND3 | P30281 | 16/20 | 0.72 |
| ▸ | CDK2 | P24941 | 9/20 | 0.72 |
| ▸ | CCNA2 | P20248 | 8/20 | 0.72 |
| ▸ | CCNE2 | O96020 | 7/20 | 0.72 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.72 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.72 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.72 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.72 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.72 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.72 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.45 |
| ▸ | CDK1 | P06493 | 3/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268115 | 0.84 | CDK4 (1.00) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL31060368 | 0.84 | CDK4 (1.00) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL5264393 | 0.84 | CDK4 (0.81) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL4715283 | 0.84 | CDK4 (1.00) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL5264399 | 0.82 | CDK4 (0.89) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL5263960 | 0.82 | CDK4 (0.91) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL5265080 | 0.82 | CDK4 (0.83) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL15984313 | 0.81 | CDK4 (0.73) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL5264187 | 0.80 | CDK4 (0.81) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL14873890 | 0.80 | CDK4 (0.77) | CDK4CCND1CCND2CCND3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975620-A2 | Three hybrid assay system | GPC Biotech AG (DE) | 2008-10-01 | — | — | EP | disclosed |