Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 1.00 |
| ▸ | EGFR | P00533 | 16/20 | 1.00 |
| ▸ | ABL1 | P00519 | 15/20 | 1.00 |
| ▸ | ABL2 | P42684 | 15/20 | 1.00 |
| ▸ | LCK | P06239 | 2/20 | 0.70 |
| ▸ | FGR | P09769 | 1/20 | 0.65 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.65 |
| ▸ | TXK | P42681 | 1/20 | 0.65 |
| ▸ | FRK | P42685 | 1/20 | 0.65 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.65 |
| ▸ | IGF1R | P08069 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8099098 | 0.99 | SRC (0.98) | SRCEGFRABL1ABL2LCK | |
| SCHEMBL8098925 | 0.94 | SRC (0.89) | SRCEGFRABL1ABL2LCK | |
| Hydrochloric Acid SCHEMBL8114119 | 0.87 | SRC (0.98) | SRCEGFRABL1ABL2LCK | |
| SCHEMBL12856462 | 0.87 | EGFR (1.00) | SRCEGFRABL1ABL2LCK | |
| SCHEMBL18521878 | 0.86 | EGFR (0.98) | SRCEGFRABL1ABL2LCK | |
| Hydrochloric Acid SCHEMBL8108003 | 0.86 | IGF1R (0.85) | SRCEGFRABL1ABL2LCK | |
| SCHEMBL7025438 | 0.85 | ABL1 (0.85) | SRCEGFRABL1ABL2LCK | |
| SCHEMBL7021405 | 0.85 | SRC (1.00) | SRCEGFRABL1ABL2LCK | |
| SCHEMBL8114105 | 0.85 | SRC (1.00) | SRCEGFRABL1ABL2LCK | |
| SCHEMBL14617844 | 0.82 | SRC (1.00) | SRCEGFRABL1ABL2LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975620-A2 | Three hybrid assay system | GPC Biotech AG (DE) | 2008-10-01 | — | — | EP | disclosed |