Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL665010 | 1.00 | ATM (0.49) | ATMKDM4EKMT2ATP53MEN1 | |
| SCHEMBL5914551 | 1.00 | ATM (0.49) | ATMKDM4EKMT2ATP53MEN1 | |
| SCHEMBL12858695 | 1.00 | ATM (0.49) | ATMKDM4EKMT2ATP53MEN1 | |
| SCHEMBL576057 | 1.00 | ATM (0.49) | ATMKDM4EKMT2ATP53MEN1 | |
| SCHEMBL13041122 | 0.88 | CYP2C9 (0.50) | ATMKDM4EKMT2ATP53MEN1 | |
| SCHEMBL16976466 | 0.88 | CYP2C9 (0.50) | ATMKDM4EKMT2ATP53MEN1 | |
| SCHEMBL5914546 | 0.88 | CYP2C9 (0.50) | ATMKDM4EKMT2ATP53MEN1 | |
| SCHEMBL12676358 | 0.88 | CYP2C9 (0.50) | ATMKDM4EKMT2ATP53MEN1 | |
| SCHEMBL5914548 | 0.88 | CYP2C9 (0.50) | ATMKDM4EKMT2ATP53MEN1 | |
| SCHEMBL5936402 | 0.86 | HTT (0.49) | ATMKDM4EKMT2ATP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3330339-A1 | COMPOSITIONS COMPRISING HFC-1234ZE | The Chemours Company FC, LLC (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-1985681-A2 | Compositions comprising a fluoroolefin | E. I. Du Pont de Nemours and Company (US) | 2008-10-29 | — | — | EP | disclosed |