Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340493 | 0.94 | ELANE (0.82) | ELANECYP2C9CYP3A4 | |
| SCHEMBL8342249 | 0.93 | ELANE (0.74) | ELANECYP2C9CYP3A4 | |
| SCHEMBL2879286 | 0.93 | ELANE (0.87) | ELANECYP2C9CYP3A4 | |
| SCHEMBL8338464 | 0.92 | ELANE (0.73) | ELANECYP2C9CYP3A4 | |
| SCHEMBL8343479 | 0.92 | ELANE (0.72) | ELANECYP2C9CYP3A4 | |
| SCHEMBL4684366 | 0.90 | ELANE (0.72) | ELANECYP2C9CYP3A4 | |
| SCHEMBL4681260 | 0.89 | ELANE (0.72) | ELANECYP2C9CYP3A4 | |
| SCHEMBL2885094 | 0.88 | ELANE (0.92) | ELANECYP2C9CYP3A4 | |
| SCHEMBL8338219 | 0.88 | ELANE (0.68) | ELANECYP2C9CYP3A4 | |
| SCHEMBL13378089 | 0.88 | ELANE (0.68) | ELANECYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537081-B1 | DIHYDROPYRIDINE DERIVATIVES FOR USE AS HUMAN NEUTROPHIL ELASTASE INHIBITORS | BAYER HEALTHCARE AG (DE) | 2008-10-15 | — | — | EP | disclosed |