Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 10/20 | 0.68 |
| ▸ | CSF1R | P07333 | 5/20 | 0.68 |
| ▸ | KIT | P10721 | 3/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | PIKFYVE | Q9Y2I7 | 2/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.54 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14042252 | 0.92 | BRAF (0.66) | BRAFCSF1RKITMAPK14KDR | |
| SCHEMBL14042661 | 0.92 | BRAF (0.65) | BRAFCSF1RKITMAPK14LCK | |
| SCHEMBL14042162 | 0.91 | BRAF (0.68) | BRAFCSF1RKITMAPK14KDR | |
| SCHEMBL14042652 | 0.91 | BRAF (0.64) | BRAFCSF1RKITMAPK14LCK | |
| SCHEMBL14042731 | 0.90 | BRAF (0.62) | BRAFCSF1RKITMAPK14LCK | |
| SCHEMBL14042164 | 0.89 | BRAF (0.65) | BRAFCSF1RKITMAPK14LCK | |
| SCHEMBL14042448 | 0.89 | BRAF (0.63) | BRAFCSF1RKITMAPK14KDR | |
| SCHEMBL14042251 | 0.88 | BRAF (0.61) | BRAFCSF1RKITMAPK14KDR | |
| SCHEMBL14042651 | 0.88 | BRAF (0.69) | BRAFCSF1RKITMAPK14KDR | |
| SCHEMBL14042445 | 0.88 | BRAF (0.59) | BRAFCSF1RKITMAPK14LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124393-A1 | BENZOTHIAZOLE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2008-10-16 | — | — | WO | disclosed |