Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.66 |
| ▸ | CDK2 | P24941 | 7/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13120539 | 0.93 | GSK3B (0.68) | GSK3BCDK2CCNE1 | |
| SCHEMBL13120533 | 0.91 | GSK3B (0.66) | GSK3BCDK2CCNE1 | |
| SCHEMBL13120513 | 0.91 | GSK3B (0.68) | GSK3BCDK2CCNE1 | |
| SCHEMBL13120529 | 0.89 | GSK3B (0.71) | GSK3BCDK2CCNE1 | |
| SCHEMBL13120526 | 0.88 | GSK3B (0.70) | GSK3BCDK2CCNE1 | |
| SCHEMBL13120528 | 0.87 | GSK3B (0.69) | GSK3BCDK2CCNE1 | |
| SCHEMBL13120538 | 0.87 | GSK3B (0.71) | GSK3BCDK2CCNE1 | |
| SCHEMBL13120562 | 0.87 | GSK3B (0.73) | GSK3BCDK2CCNE1 | |
| SCHEMBL13120534 | 0.86 | GSK3B (0.71) | GSK3BCDK2CCNE1 | |
| SCHEMBL13120511 | 0.86 | GSK3B (0.71) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130570-A1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |