Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 7/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953866 | 0.91 | GSK3B (0.54) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL12954380 | 0.91 | GSK3B (0.68) | GSK3BCDK2CCNE1 | |
| SCHEMBL12953701 | 0.90 | GSK3B (0.55) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL14307159 | 0.85 | GSK3B (0.52) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL14581985 | 0.84 | GSK3B (0.61) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL13288625 | 0.83 | GSK3B (0.56) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL13288831 | 0.83 | GSK3B (0.59) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL13289048 | 0.83 | GSK3B (0.59) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL13288822 | 0.83 | GSK3B (0.55) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL12954326 | 0.82 | GSK3B (0.58) | GSK3BCHEK1CDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130570-A1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |