Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875184 | 0.82 | HCAR2 (0.72) | LMNADAOHCAR2KMT2AALDH1A1 | |
| Water SCHEMBL6228901 | 0.80 | KMT2A (0.72) | KDM4ELMNAKMT2AALDH1A1CES2 | |
| SCHEMBL31369148 | 0.78 | KMT2A (0.75) | KDM4ELMNAKMT2AALDH1A1CES2 | |
| SCHEMBL87791 | 0.78 | KMT2A (0.75) | KDM4ELMNAKMT2AALDH1A1CES2 | |
| SCHEMBL31369119 | 0.76 | KMT2A (0.72) | KDM4ELMNAKMT2AALDH1A1CES2 | |
| Charcoal, Activated SCHEMBL8358164 | 0.76 | KMT2A (0.72) | KDM4ELMNAKMT2AALDH1A1CES2 | |
| Hydrochloric Acid SCHEMBL27723543 | 0.76 | KMT2A (0.72) | KDM4ELMNAKMT2AALDH1A1CES2 | |
| SCHEMBL13184406 | 0.76 | KMT2A (0.49) | KDM4ELMNAKMT2AALDH1A1CES2 | |
| Acetic Acid SCHEMBL28040553 | 0.75 | KMT2A (0.70) | KDM4ELMNAKMT2AALDH1A1CES2 | |
| Alcohol SCHEMBL9405122 | 0.73 | KMT2A (0.62) | KDM4ELMNAKMT2AALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435831-B2 | Bicyclic and bridged nitrogen heterocycles | CHEMOCENTRYX, INC. (US) | 2008-10-14 | — | — | US | disclosed |