Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.52 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19223473 | 0.85 | IDO1 (0.55) | IDO1GGPS1CYP3A4MAPK1CYP1A2 | |
| SCHEMBL6886022 | 0.80 | GGPS1 (0.55) | IDO1GGPS1CYP3A4MAPK1CYP1A2 | |
| SCHEMBL14040511 | 0.77 | IDO1 (0.48) | IDO1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14018901 | 0.77 | IDO1 (0.48) | IDO1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3030151 | 0.77 | GGPS1 (0.56) | IDO1GGPS1CYP3A4MAPK1CYP1A2 | |
| SCHEMBL3030149 | 0.77 | GGPS1 (0.56) | IDO1GGPS1CYP3A4MAPK1CYP1A2 | |
| SCHEMBL19308329 | 0.76 | GGPS1 (0.50) | IDO1GGPS1CYP3A4MAPK1CYP1A2 | |
| SCHEMBL11361556 | 0.74 | GGPS1 (0.56) | IDO1GGPS1CYP3A4MAPK1CYP1A2 | |
| SCHEMBL14040447 | 0.72 | SLC6A4 (0.69) | IDO1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29018294 | 0.72 | GGPS1 (0.50) | IDO1GGPS1CYP3A4MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008125230-A2 | INSECTICIDAL DERIVATIVES OF SUBSTITUTED AMINOHETEROCYCLES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | disclosed |