Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL5826150 | 0.96 | CA4 (0.50) | CA4CA1TDP1ALDH1A1FAHD1 | |
| Methacrylic Acid SCHEMBL19384595 | 0.96 | CA4 (0.57) | CA4CA1TDP1ALDH1A1FAHD1 | |
| Methacrylic Acid SCHEMBL59390 | 0.96 | — | — | |
| Methacrylic Acid SCHEMBL7559355 | 0.93 | CA4 (0.67) | CA4CA1TDP1ALDH1A1FAHD1 | |
| Methacrylic Acid SCHEMBL23175214 | 0.92 | CA4 (0.53) | CA4CA1TDP1ALDH1A1FAHD1 | |
| Methacrylic Acid SCHEMBL672275 | 0.92 | CA4 (0.53) | CA4CA1TDP1ALDH1A1FAHD1 | |
| Methacrylic Acid SCHEMBL3145701 | 0.92 | CA4 (0.53) | CA4CA1TDP1ALDH1A1FAHD1 | |
| Methacrylic Acid SCHEMBL11614214 | 0.92 | CA4 (0.53) | CA4CA1TDP1ALDH1A1FAHD1 | |
| Methacrylic Acid SCHEMBL20582675 | 0.92 | CA4 (0.53) | CA4CA1TDP1ALDH1A1FAHD1 | |
| Methacrylic Acid SCHEMBL10484391 | 0.92 | CA4 (0.53) | CA4CA1TDP1ALDH1A1FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2827 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080805-A | Acid corrosion resistant insulating black smoke adhesive and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-12421430-B2 | Composition based on (meth)acrylate monomers | BOSTIK SA (FR) | 2025-09-23 | — | — | US | claimed |
| US-12371444-B2 | Methods of making MOFs, systems for synthesizing MOFs, and methods of coating textiles with MOFs | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2025-07-29 | — | — | US | claimed |
| CN-120158022-A | Polymethacrylimide wave-absorbing foam and preparation method thereof | 湖南兆恒材料科技有限公司 | 2025-06-17 | — | — | CN | claimed |
| WO-2025107234-A1 | POLYACRYLATE MATERIAL AND PREPARATION METHOD THEREFOR | 广州工程技术职业学院 | 2025-05-30 | — | — | WO | claimed |
| CN-116096809-B | Rubber composition based on highly saturated diene elastomer | 米其林集团总公司 | 2025-05-30 | — | — | CN | claimed |
| CN-119978578-A | Hydrogenated nitrile rubber composition, vulcanized rubber, preparation method of vulcanized rubber and application of vulcanized rubber in automobile synchronous belt | 中国石油化工股份有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119552431-A | Rubber bushing sizing material and preparation method thereof | 常州朗博密封科技股份有限公司 | 2025-03-04 | — | — | CN | claimed |
| CN-116023723-B | Hydrogenated nitrile rubber composition and application thereof, vulcanized rubber and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119463392-A | Foamable composition, biodegradable PMI foam and preparation method thereof | 浩博（福建）新材料科技有限公司 | 2025-02-18 | — | — | CN | claimed |
| US-4720526-A | Cured rubber compositions of high modulus | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-01-19 | — | — | US | claimed |
| EP-0248271-A1 | Cured rubber compositions of high modulus | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1987-12-09 | — | — | EP | claimed |
| EP-0119713-B1 | LIQUID ELECTROGRAPHIC DEVELOPERS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-10-07 | — | — | EP | claimed |
| US-4665104-A | POLYMETHACRYLIMIDE | ROHM GMBH (DE) | 1987-05-12 | — | — | US | claimed |
| US-4647951-A | PROTECTIVE COATINGS, WATER SOLUBILITY, RESINS, POLYALUMINUM HYDROXIDE, UNSATURATED ACID SALT | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1987-03-03 | — | — | US | claimed |
| US-4547449-A | IMPROVED REPLENISHABILITY | EASTMAN KODAK COMPANY (US) | 1985-10-15 | — | — | US | claimed |
| US-4483537-A | POLYBUTADIENE CORE CROSSLINKED WITH(METH)ACRYLIC ACID AND A POLYFUNCTIONAL (METH) ACRYLATE, IONOMER-METAL (METH) ACRYLATE SHELL | HAYAKAWA RUBBER CO., LTD. (JP) | 1984-11-20 | — | — | US | claimed |
| EP-0119713-A1 | Liquid electrographic developers | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-09-26 | — | — | EP | claimed |
| US-4410648-A | CYCLIC ANHYDRIDE OR IMIDE, INORGANIC POWDER, POLYUNSATURATED MONOMER | DAINICHI-NIPPON CABLES, LTD. (JP) | 1983-10-18 | — | — | US | claimed |
| US-4025391-A | FREEZING A SOLUTION OF AN ENZYME AND A WATER-SOLUBLE MONOMER OR POLYMER POLYMERIZATION WITH IONIZING RADIATION | DIRECTOR OF NATIONAL FOOD RESEARCH INSTITUTE (JA) | 1977-05-24 | — | — | US | claimed |