SCHEMBL1404472

SCHEMBL1404472

CCN(C(N)=S)S(=O)(=O)O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.33
PHGDH O43175 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27656279 0.70 CHRM1 (0.32)
Hydrochloric Acid SCHEMBL11227232 0.68 CHRM2 (0.31)
SCHEMBL2416240 0.68
SCHEMBL8431685 0.65 NPSR1 (0.36) NPSR1
SCHEMBL28555638 0.64
Methane SCHEMBL10750525 0.64 BLM (0.35) NPSR1
SCHEMBL244841 0.62
SCHEMBL8663660 0.62
SCHEMBL11673924 0.62 EHMT2 (0.36) NPSR1PHGDHMGLL
SCHEMBL96554 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8084638-B2 Sulfanyl derivatives and their use as synthesis intermediates UCB PHARMA, S.A. (BE) 2011-12-27 US disclosed
EP-2173708-B1 SULFANYL DERIVATIVES AND THEIR USE AS SYNTHESIS INTERMEDIATES UCB PHARMA SA (BE) 2011-03-09 EP disclosed
US-20100292505-A1 Sulfanyl Derivatives And Their Use As Synthesis Intermediates UCB PHARMA, S.A. (BE) 2010-11-18 US disclosed
EP-2173708-A1 SULFANYL DERIVATIVES AND THEIR USE AS SYNTHESIS INTERMEDIATES UCB Pharma, S.A. (BE) 2010-04-14 EP disclosed
WO-2009019119-A1 SULFANYL DERIVATIVES AND THEIR USE AS SYNTHESIS INTERMEDIATES UCB PHARMA S.A. (BE) 2009-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292505-A1 Sulfanyl Derivatives And Their Use As Synthesis Intermediates CACNA1A, KCNN1, KCNN2 NPSR1 87/4885PHGDH 1597/4885MGLL 3803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.