Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14044947 | 1.00 | F10 (0.47) | F10LMNAMAPK1KMT2AWDR91 | |
| SCHEMBL3308362 | 1.00 | F10 (0.47) | F10LMNAMAPK1KMT2AWDR91 | |
| SCHEMBL3309229 | 0.96 | F10 (0.50) | F10LMNAMAPK1KMT2AWDR91 | |
| SCHEMBL13394917 | 0.93 | F10 (0.47) | F10LMNAMAPK1KMT2AWDR91 | |
| SCHEMBL3339773 | 0.91 | F10 (0.46) | F10LMNAMAPK1KMT2AWDR91 | |
| SCHEMBL13394956 | 0.91 | F10 (0.45) | F10LMNAMAPK1KMT2AWDR91 | |
| SCHEMBL3308991 | 0.90 | F10 (0.46) | F10LMNAMAPK1KMT2AWDR91 | |
| SCHEMBL13394967 | 0.90 | F10 (0.46) | F10LMNAMAPK1KMT2AWDR91 | |
| SCHEMBL13394962 | 0.90 | F10 (0.46) | F10LMNAMAPK1KMT2AWDR91 | |
| SCHEMBL3308996 | 0.90 | F10 (0.46) | F10LMNAMAPK1KMT2AWDR91 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116881-A1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-02 | — | — | WO | disclosed |