Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14045450 | 0.99 | CYSLTR1 (0.45) | CYSLTR1CYSLTR2GPBAR1ALOX5APALOX5 | |
| SCHEMBL14045446 | 0.97 | CYSLTR1 (0.43) | CYSLTR1CYSLTR2GPBAR1ALOX5APALOX5 | |
| SCHEMBL14045430 | 0.89 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL4850064 | 0.88 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL4848359 | 0.87 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL14045431 | 0.87 | CYSLTR1 (0.39) | CYSLTR1CYSLTR2GPBAR1ALOX5APALOX5 | |
| SCHEMBL4846550 | 0.86 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1ALOX5AP | |
| SCHEMBL4848377 | 0.85 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1ALOX5AP | |
| SCHEMBL4841446 | 0.85 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2GPBAR1CYP1A2 | |
| SCHEMBL4844970 | 0.83 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1ALOX5APCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |