Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.36 |
| ▸ | FEN1 | P39748 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | FGB | P02675 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14092100 | 0.89 | PPIA (0.36) | ALOX5APFEN1SLC6A2ALDH1A1L3MBTL1 | |
| SCHEMBL18517443 | 0.82 | MEN1 (0.35) | ALOX5APFEN1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL14092081 | 0.82 | MEN1 (0.35) | ALOX5APFEN1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL14046822 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL14046818 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL14092245 | 0.75 | KDM4E (0.35) | ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15291928 | 0.75 | KDM4E (0.35) | ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL17849172 | 0.75 | KDM4E (0.35) | ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15291929 | 0.74 | SLC13A5 (0.30) | — | |
| SCHEMBL8537336 | 0.70 | FFAR4 (0.37) | ALOX5APFEN1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130464-A1 | MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME | TRANZYME PHARMA, INC. (US) | 2008-10-30 | — | — | WO | disclosed |