Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 14/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242641 | 0.91 | SCD (0.58) | SCDPKMROCK2 | |
| SCHEMBL242710 | 0.88 | SCD (0.61) | SCDROCK2KDM4EALDH1A1CYP3A4 | |
| SCHEMBL245005 | 0.87 | SCD (0.60) | SCDHDAC1 | |
| SCHEMBL4565193 | 0.81 | SCD (0.49) | SCDPKMHDAC1ROCK2 | |
| SCHEMBL241054 | 0.81 | SCD (0.61) | SCDHDAC1 | |
| SCHEMBL348495 | 0.80 | SCD (0.56) | SCD | |
| SCHEMBL242539 | 0.79 | SCD (0.78) | SCD | |
| SCHEMBL241977 | 0.78 | SCD (0.64) | SCDHDAC1 | |
| SCHEMBL246305 | 0.78 | SCD (0.82) | SCD | |
| SCHEMBL240479 | 0.77 | SCD (0.62) | SCDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127349-A2 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LIPID LEVEL | NOVARTIS AG (CH) | 2008-10-23 | — | — | WO | disclosed |