Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962153 | 0.91 | MAP2K1 (0.59) | MAP2K1RAF1 | |
| SCHEMBL12694063 | 0.89 | MAP2K1 (0.61) | MAP2K1RAF1 | |
| SCHEMBL960362 | 0.88 | MAP2K1 (0.74) | MAP2K1RAF1 | |
| SCHEMBL12694070 | 0.83 | MAP2K1 (0.79) | MAP2K1RAF1 | |
| SCHEMBL961297 | 0.80 | MAP2K1 (0.63) | MAP2K1RAF1 | |
| SCHEMBL960913 | 0.80 | MAP2K1 (0.63) | MAP2K1RAF1 | |
| SCHEMBL959760 | 0.80 | MAP2K1 (0.63) | MAP2K1RAF1 | |
| SCHEMBL963953 | 0.80 | MAP2K1 (0.62) | MAP2K1RAF1 | |
| SCHEMBL962584 | 0.80 | MAP2K1 (0.62) | MAP2K1RAF1 | |
| SCHEMBL963514 | 0.79 | MAP2K1 (0.76) | MAP2K1RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982982-A1 | NOVEL COUMARIN DERIVATIVE HAVING ANTITUMOR ACTIVITY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-10-22 | — | — | EP | disclosed |