Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14136979 | 0.89 | KDM4E (0.48) | OPRD1OPRM1KDM4EMEN1NPC1 | |
| SCHEMBL14030874 | 0.88 | MKNK1 (0.37) | OPRD1IKBKBMKNK1KDM4ECHEK1 | |
| SCHEMBL14048985 | 0.85 | SMN1; SMN2 (0.44) | ACHEMEN1NPC1RAB9AKMT2A | |
| SCHEMBL14049088 | 0.83 | CHEK1 (0.42) | OPRD1OPRM1CHEK1 | |
| SCHEMBL2876357 | 0.80 | CYP2E1 (0.42) | MKNK1KDM4ECHEK1 | |
| Hydrochloric Acid SCHEMBL2874873 | 0.79 | CYP2E1 (0.41) | MKNK1KDM4ECHEK1 | |
| SCHEMBL2870751 | 0.77 | KDM4E (0.47) | MKNK1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL14136980 | 0.76 | SMN1; SMN2 (0.44) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL14049048 | 0.75 | IKBKB (0.40) | OPRD1OPRM1IKBKBKDM4ENPC1 | |
| SCHEMBL14030873 | 0.74 | SMN1; SMN2 (0.43) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269481-A1 | Compounds and methods for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC. (CA) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269481-A1 | Compounds and methods for the treatment or prevention of Flavivirus infections | ZC3HAV1, ZYX, ZFX | OPRD1 4221/4885OPRM1 4348/4885ACHE 1874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.