Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 8/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14049173 | 0.94 | SLC5A2 (0.47) | SLC5A2PTGESALOX5PSEN1SSTR1 | |
| SCHEMBL14544877 | 0.93 | SLC5A2 (0.49) | SLC5A2PTGESALOX5PSEN1SSTR1 | |
| SCHEMBL14544800 | 0.92 | SLC5A2 (0.51) | SLC5A2PTGESALOX5PSEN1SSTR1 | |
| SCHEMBL14544894 | 0.92 | SLC5A2 (0.47) | SLC5A2PTGESALOX5PSEN1SSTR1 | |
| SCHEMBL14545123 | 0.91 | SLC5A2 (0.58) | SLC5A2PTGESALOX5PSEN1SSTR1 | |
| SCHEMBL14544879 | 0.91 | SLC5A2 (0.46) | SLC5A2PTGESALOX5PSEN1SSTR1 | |
| SCHEMBL14544878 | 0.89 | SLC5A2 (0.48) | SLC5A2PTGESALOX5PSEN1SSTR1 | |
| SCHEMBL14544803 | 0.89 | SLC5A2 (0.47) | SLC5A2PTGESALOX5PSEN1NAMPT | |
| SCHEMBL12425888 | 0.89 | SLC5A2 (0.47) | SLC5A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL14545126 | 0.88 | SLC5A2 (0.47) | SLC5A2PTGESALOX5PSEN1SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1980560-A2 | C-glycoside derivatives for the treatment of diabetes | Astellas Pharma Inc. (JP) | 2008-10-15 | — | — | EP | disclosed |
| US-7202350-B2 | C-glycoside derivatives and salts thereof | ASTELLAS PHARMA INC. (JP) | 2007-04-10 | — | — | US | disclosed |