Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 4/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.30 |
| ▸ | MMP3 | P08254 | 2/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14031132 | 0.86 | GAA (0.35) | GAAF2F10PRSS1NAAA | |
| SCHEMBL8019153 | 0.83 | GAA (0.35) | GAAF2F10PRSS1BACE1 | |
| SCHEMBL14049098 | 0.78 | ADRB3 (0.39) | PDE4BADRB3ADRA2BADRA2C | |
| SCHEMBL8138362 | 0.77 | ADRB3 (0.42) | GAAF2F10PRSS1PDE4B | |
| SCHEMBL7940307 | 0.77 | ADRB3 (0.42) | GAAF2F10PRSS1PDE4B | |
| SCHEMBL15487382 | 0.77 | ADRB3 (0.42) | GAAF2F10PRSS1PDE4B | |
| SCHEMBL3373243 | 0.77 | ADRB3 (0.42) | GAAF2F10PRSS1PDE4B | |
| SCHEMBL3373249 | 0.77 | ADRB3 (0.42) | GAAF2F10PRSS1PDE4B | |
| SCHEMBL13784408 | 0.77 | F2 (0.33) | GAAF2F10PRSS1NAAA | |
| SCHEMBL20115685 | 0.76 | F2 (0.32) | GAAF2F10PRSS1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442695-B2 | Depeptidized inhibitors of hepatitis C virus NS3 protease | SCHERING CORPORATION (US) | 2008-10-28 | — | — | US | disclosed |