⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13384019 | 1.00 | — | — | |
| SCHEMBL12222439 | 1.00 | — | — | |
| SCHEMBL22800140 | 0.85 | — | — | |
| SCHEMBL14428809 | 0.83 | — | — | |
| SCHEMBL15978349 | 0.78 | CNR1 (0.34) | — | |
| SCHEMBL15978351 | 0.78 | CNR1 (0.34) | — | |
| SCHEMBL16638837 | 0.77 | — | — | |
| SCHEMBL14012435 | 0.77 | — | — | |
| SCHEMBL12230293 | 0.77 | — | — | |
| SCHEMBL13871540 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123083-A1 | DOUBLE-STRANDED NUCLEIC ACID INHIBITOR MOLECULES CONTAINING A TRILOOP | DICERNA PHARMACEUTICALS, INC. (US) | 2020-06-18 | — | — | WO | disclosed |
| WO-2019200124-A1 | DOUBLE-STRANDED NUCLEIC ACID INHIBITOR MOLECULES MODIFIED WITH TM-INCREASING NUCLEOTIDES | DICERNA PHARMACEUTICALS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |
| WO-2019079472-A1 | BETA CATENIN NUCLEIC ACID INHIBITOR MOLECULE | DICERNA PHARMACEUTICALS, INC. (US) | 2019-04-25 | — | — | WO | disclosed |
| US-9803240-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-20140194611-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-20120329677-A9 | ARRAYS OF NUCLEIC ACID PROBES FOR DETECTING CYSTIC FIBROSIS | AFFYMETRIX, INC. | 2012-12-27 | — | — | US | disclosed |
| US-20080261832-A1 | Arrays of nucleic acid probes for detecting cystic fibrosis | CRONIN MAUREEN T | 2008-10-23 | — | — | US | disclosed |
| US-7399584-B2 | Method of comparing a target nucleic acid and a reference nucleic acid | AFFYMETRIX, INC. (US) | 2008-07-15 | — | — | US | disclosed |
| US-20070060744-A1 | Process for the synthesis of pyrazolopyrimidines | EPOCH BIOSCIENCES, INC. (US) | 2007-03-15 | — | — | US | disclosed |