Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.33 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14049687 | 0.95 | TRPV1 (0.39) | TRPV1PTPN1NR1H4HSD17B10TDP1 | |
| SCHEMBL14049668 | 0.93 | TRPV1 (0.40) | TRPV1PTPN1NR1H4HSD17B10TDP1 | |
| SCHEMBL14049662 | 0.90 | PTPN1 (0.39) | TRPV1PTPN1NR1H4HSD17B10TDP1 | |
| SCHEMBL14049663 | 0.89 | HSD17B10 (0.42) | TRPV1PTPN1NR1H4HSD17B10TDP1 | |
| SCHEMBL14049852 | 0.89 | TRPV1 (0.41) | TRPV1PTPN1NR1H4HSD17B10TDP1 | |
| SCHEMBL14049842 | 0.89 | TRPV1 (0.39) | TRPV1PTPN1NR1H4HSD17B10TDP1 | |
| SCHEMBL14049865 | 0.89 | PTPN1 (0.40) | TRPV1PTPN1NR1H4HSD17B10TDP1 | |
| SCHEMBL14049980 | 0.88 | TRPV1 (0.39) | TRPV1PTPN1NR1H4HSD17B10TDP1 | |
| SCHEMBL14049675 | 0.88 | PTPN1 (0.40) | TRPV1PTPN1NR1H4HSD17B10TDP1 | |
| SCHEMBL14049841 | 0.88 | TRPV1 (0.39) | TRPV1PTPN1NR1H4HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127364-A2 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MYRIAD GENETICS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |