Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 6/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14049921 | 0.90 | HSD17B10 (0.55) | HSD17B10TDP1LMNATRPV1RORC | |
| SCHEMBL13628477 | 0.88 | GPBAR1 (0.58) | GPBAR1LMNANT5ESMN1; SMN2TRPV1 | |
| SCHEMBL13637791 | 0.88 | GPBAR1 (0.58) | GPBAR1LMNANT5ESMN1; SMN2TRPV1 | |
| SCHEMBL14049776 | 0.80 | HSD17B10 (0.56) | HSD17B10TDP1LMNATRPV1RORC | |
| SCHEMBL14049838 | 0.79 | HSD17B10 (0.56) | HSD17B10TDP1GPBAR1LMNANT5E | |
| SCHEMBL14049785 | 0.79 | HSD17B10 (0.58) | HSD17B10TDP1GPBAR1LMNANT5E | |
| SCHEMBL13628320 | 0.79 | TRPV1 (0.66) | GPBAR1LMNANT5ETRPV1RORC | |
| SCHEMBL13637465 | 0.79 | TRPV1 (0.66) | GPBAR1LMNANT5ETRPV1RORC | |
| SCHEMBL4445877 | 0.79 | TRPV1 (0.66) | GPBAR1LMNANT5ETRPV1RORC | |
| SCHEMBL13628322 | 0.78 | TRPV1 (0.65) | GPBAR1LMNANT5ETRPV1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127364-A2 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MYRIAD GENETICS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |