Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 12/20 | 0.48 |
| ▸ | CDK9 | P50750 | 12/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | ABL2 | P42684 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | CDK7 | P50613 | 1/20 | 0.48 |
| ▸ | CCNH | P51946 | 1/20 | 0.48 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8514605 | 0.92 | CCNT1 (0.46) | CCNT1CDK9MAP4K4CDK1CDK4 | |
| SCHEMBL8515516 | 0.91 | CCNT1 (0.47) | CCNT1CDK9MAP4K4CDK1CDK4 | |
| SCHEMBL8515470 | 0.85 | CCNT1 (0.47) | CCNT1CDK9MAP4K4CDK1CDK4 | |
| SCHEMBL2991912 | 0.84 | CYP2D6 (0.44) | CCNT1CDK9MAP4K4CDK1CDK4 | |
| SCHEMBL8516305 | 0.82 | CYP1A2 (0.52) | CCNT1CDK9MAP4K4CDK1CDK4 | |
| SCHEMBL4438331 | 0.82 | CCNT1 (0.55) | CCNT1CDK9MAP4K4CDK1CDK4 | |
| SCHEMBL8515521 | 0.80 | CYP1A2 (0.53) | CCNT1CDK9MAP4K4CDK1CDK4 | |
| SCHEMBL4437883 | 0.80 | CDK1 (0.53) | CCNT1CDK9MAP4K4CDK1CDK4 | |
| SCHEMBL2998016 | 0.78 | CCNT1 (0.46) | CCNT1CDK9MAP4K4CDK1CDK4 | |
| SCHEMBL8515479 | 0.77 | CCNT1 (0.48) | CCNT1CDK9MAP4K4CDK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129080-A1 | 4, 6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES | INGENIUM PHARMACEUTICALS GMBH (DE) | 2008-10-30 | — | — | WO | disclosed |