Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 15/20 | 0.64 |
| ▸ | CDK2 | P24941 | 6/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13119183 | 0.92 | GSK3B (0.65) | GSK3BCDK2CCNE1 | |
| SCHEMBL12952884 | 0.86 | GSK3B (0.73) | GSK3BCDK2CCNE1 | |
| SCHEMBL13118912 | 0.85 | GSK3B (0.69) | GSK3BCDK2CCNE1 | |
| SCHEMBL13288630 | 0.85 | GSK3B (0.55) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119131 | 0.85 | GSK3B (0.65) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119103 | 0.84 | GSK3B (0.70) | GSK3BCDK2CCNE1 | |
| SCHEMBL14607095 | 0.83 | GSK3B (0.63) | GSK3BCDK2CCNE1 | |
| SCHEMBL12954506 | 0.83 | GSK3B (0.69) | GSK3BCDK2CCNE1 | |
| SCHEMBL12953563 | 0.83 | GSK3B (0.71) | GSK3BCDK2CCNE1 | |
| SCHEMBL12952868 | 0.83 | GSK3B (0.73) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130569-A1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |