Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.53 |
| ▸ | CDK2 | P24941 | 7/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR39 | O43194 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13305704 | 0.90 | GSK3B (0.53) | GSK3BCDK2CCNA2CCNA1HPGD | |
| SCHEMBL12953964 | 0.90 | GSK3B (0.67) | GSK3BCDK2CCNA2CCNA1HPGD | |
| SCHEMBL13305188 | 0.85 | GSK3B (0.63) | GSK3BCDK2CCNA2CCNA1GPR39 | |
| SCHEMBL13304910 | 0.85 | GSK3B (0.60) | GSK3BCDK2CCNA2CCNA1GPR39 | |
| SCHEMBL13305403 | 0.84 | GSK3B (0.59) | GSK3BCDK2CCNA2CCNA1GPR39 | |
| SCHEMBL12953772 | 0.83 | GSK3B (0.68) | GSK3BCDK2CCNA2CCNA1MAPK10 | |
| SCHEMBL13305706 | 0.83 | GSK3B (0.54) | GSK3BCDK2CCNA2CCNA1GPR39 | |
| SCHEMBL14050900 | 0.82 | GSK3B (0.61) | GSK3BCDK2CCNA2CCNA1GPR39 | |
| SCHEMBL12953767 | 0.82 | GSK3B (0.69) | GSK3BCDK2CCNA2CCNA1CCNE1 | |
| SCHEMBL13305398 | 0.82 | GSK3B (0.54) | GSK3BCDK2CCNA2CCNA1GPR39 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130569-A1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |