Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405590 | 1.00 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL488984 | 0.92 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL488983 | 0.92 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL489137 | 0.88 | HRH3 (0.47) | HRH3KCNH2 | |
| SCHEMBL489138 | 0.88 | HRH3 (0.47) | HRH3KCNH2 | |
| SCHEMBL1405634 | 0.85 | HRH3 (0.56) | HRH3KCNH2 | |
| SCHEMBL1405633 | 0.85 | HRH3 (0.56) | HRH3KCNH2 | |
| SCHEMBL489320 | 0.85 | HRH3 (0.52) | HRH3KCNH2 | |
| SCHEMBL489319 | 0.85 | HRH3 (0.52) | HRH3KCNH2 | |
| SCHEMBL6704594 | 0.84 | HRH3 (0.58) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620434-B1 | FUSED BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LAB (US) | 2011-03-09 | — | — | EP | claimed |