SCHEMBL1405623

SCHEMBL1405623

CC(=O)Nc1ccc(N=Nc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 1.00
RAB9A P51151 7/20 1.00
NPC1 O15118 6/20 1.00
SMN1; SMN2 Q16637 6/20 1.00
LMNA P02545 4/20 0.73
HPGD P15428 2/20 0.73
NFKB1 P19838 1/20 0.73
NFKB2 Q00653 1/20 0.73
RELA Q04206 1/20 0.73
NAPRT Q6XQN6 1/20 0.67
HSD17B10 Q99714 1/20 0.67
KMT2A Q03164 8/20 0.63
TAAR1 Q96RJ0 1/20 0.63
POLB P06746 1/20 0.63
MEN1 O00255 7/20 0.62
ALDH1A1 P00352 6/20 0.62
HTT P42858 3/20 0.62
KDM4E B2RXH2 1/20 0.62
TDP1 Q9NUW8 2/20 0.61
MAPK1 P28482 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27973101 1.00 MAPT (1.00) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL1405622 1.00 MAPT (1.00) MAPTRAB9ANPC1SMN1; SMN2LMNA
Azobenzene SCHEMBL9735170 0.94 MAPT (0.89) MAPTRAB9ANPC1SMN1; SMN2LMNA
Azobenzene SCHEMBL9735165 0.94 MAPT (0.89) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL11649000 0.92 MAPT (0.85) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL11648995 0.92 MAPT (0.85) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL19272225 0.92 MAPT (0.85) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL19227683 0.86 SMN1; SMN2 (0.76) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL23259443 0.85 MAPT (1.00) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL19272272 0.85 MAPT (1.00) MAPTRAB9ANPC1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113480454-A Linear hydrogen bond type azobenzene crystal and preparation method and application thereof 东南大学 2021-10-08 CN claimed
EP-2908843-B1 TREATING CANCER AGENCY SCIENCE TECH & RES (SG) 2019-09-04 EP claimed
US-9889180-B2 Method of treating cancer AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-02-13 US claimed
US-20150258175-A1 METHOD OF TREATING CANCER AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-09-17 US claimed
CN-113480454-B Linear hydrogen bond type azobenzene crystal and preparation method and application thereof 东南大学 2022-08-26 CN disclosed
CN-113480454-A Linear hydrogen bond type azobenzene crystal and preparation method and application thereof 东南大学 2021-10-08 CN disclosed
WO-2021074275-A1 EFFECTIVE PHOTOMODULATION OF LANTHANIDE (III) ION LUMINESCENCE IN THE VISIBLE OR NEAR-INFRARED RANGE UNIVERSITE DE RENNES 1 (FR) 2021-04-22 WO disclosed
CN-108273478-B Formaldehyde removal composition and product 李怀玉 2021-03-02 CN disclosed
EP-2908843-B1 TREATING CANCER AGENCY SCIENCE TECH & RES (SG) 2019-09-04 EP disclosed
US-9889180-B2 Method of treating cancer AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-02-13 US disclosed
US-9868873-B2 Photochromic security enabled ink for digital offset printing applications XEROX CORPORATION (US) 2018-01-16 US disclosed
US-9791399-B2 Derivatization of carbon SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2017-10-17 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed
US-4304614-A AMMUNITION, DYNAMIC LASERS, FUSES, WELDING WALKER FRANKLIN E 1981-12-08 US disclosed
US-4296256-A 2-Decarboxy-2-hydroxymethyl-19-keto-PG compounds THE UPJOHN COMPANY (US) 1981-10-20 US disclosed
US-4196026-A LOW MOLECULAR WEIGHT WALKER FRANKLIN E 1980-04-01 US disclosed
US-4058607-A DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES AIRWICK INDUSTRIES, INC. (US) 1977-11-15 US disclosed
US-3966900-A INSECTICIDES AIRWICK INDUSTRIES, INC. (US) 1976-06-29 US disclosed