⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405926 | 1.00 | — | — | |
| Diethyl Maleate SCHEMBL7743775 | 0.91 | HCAR2 (0.64) | — | |
| Diethyl Maleate SCHEMBL7743777 | 0.91 | HCAR2 (0.64) | — | |
| SCHEMBL17019599 | 0.83 | HCAR2 (0.67) | — | |
| SCHEMBL264771 | 0.83 | — | — | |
| SCHEMBL691584 | 0.83 | — | — | |
| SCHEMBL94678 | 0.83 | — | — | |
| Diethyl Maleate SCHEMBL28432840 | 0.82 | HCAR2 (0.73) | — | |
| SCHEMBL10818991 | 0.82 | HCAR2 (0.61) | — | |
| SCHEMBL11000879 | 0.82 | MAPT (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4501932-A2 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| US-12209102-B2 | Heterocyclic compounds and uses thereof | KUMQUAT BIOSCIENCES INC. (US) | 2025-01-28 | — | — | US | disclosed |
| EP-4489738-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | Kumquat Biosciences Inc. (US) | 2025-01-15 | — | — | EP | disclosed |
| US-20240425522-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-12-26 | — | — | US | disclosed |
| US-20240425525-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-12-26 | — | — | US | disclosed |
| EP-3880208-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2024-11-20 | — | — | EP | disclosed |
| CN-111989321-B | KRAS G12C inhibitors | 米拉蒂治疗股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-20240101553-A1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2024-03-28 | — | — | US | disclosed |
| US-20230373999-A1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-11-23 | — | — | US | disclosed |
| US-20230373999-A1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-11-23 | — | — | US | disclosed |
| WO-2004015132-A2 | ENZYMATIC PROCESSES FOR THE PRODUCTION OF 4-SUBSTITUTED 3-HYDROXYBUTYRIC ACID DERIVATIVES | CODEXIS, INC. (US) | 2004-02-19 | — | — | WO | disclosed |
| EP-1161226-A4 | PHOSPHOCHOLINE LINKED PRODRUG DERIVATIVES | SUPERGEN INC (US) | 2002-04-10 | — | — | EP | disclosed |
| EP-1161226-A1 | PHOSPHOCHOLINE LINKED PRODRUG DERIVATIVES | SuperGen, Inc. (US) | 2001-12-12 | — | — | EP | disclosed |
| US-6140527-A | Process for producing butyric ester derivatives | KANEKA CORPORATION (JP) | 2000-10-31 | — | — | US | disclosed |
| WO-2000048572-A1 | PHOSPHOCHOLINE LINKED PRODRUG DERIVATIVES | SUPERGEN, INC (US) | 2000-08-24 | — | — | WO | disclosed |
| EP-0970947-A1 | PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES | KANEKA CORPORATION (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0548639-B1 | The use of polyacetals based on vinylethers and dihydroxy compounds in detergent compositions | BASF AG (DE) | 1998-06-10 | — | — | EP | disclosed |
| EP-0663932-B1 | USE OF POLYACETALS CONTAINING ACETALDEHYDE ACETAL UNITS IN WASHING AND CLEANING AGENTS | BASF AG (DE) | 1997-05-07 | — | — | EP | disclosed |
| EP-0667878-B1 | BLOCK COPOLYACETALS, PROCESS FOR PRODUCING THE SAME AND THEIR USE IN WASHING AND CLEANING AGENTS | BASF AG (DE) | 1997-01-02 | — | — | EP | disclosed |
| EP-0548639-A2 | Polyacetals based on vinylethers and dihydroxy compounds and their use in detergent compositions | BASF Aktiengesellschaft (DE) | 1993-06-30 | — | — | EP | disclosed |