SCHEMBL14062829

SCHEMBL14062829

COBNC(C)C(=S)NCc1cccc(-n2nc(C(F)(F)F)cc2C(=O)NCc2ccccc2OC)c1

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5066885 0.90 CARM1 (0.68) CARM1
SCHEMBL5066880 0.90 CARM1 (0.68) CARM1
SCHEMBL14012662 0.88 CARM1 (0.60) CARM1
SCHEMBL5064289 0.87 CARM1 (0.58) CARM1
SCHEMBL5064295 0.87 CARM1 (0.58) CARM1
SCHEMBL14565432 0.84 CARM1 (0.80) CARM1
SCHEMBL14012663 0.84 CARM1 (0.77) CARM1
SCHEMBL4563996 0.82 CARM1 (0.72) CARM1
SCHEMBL5066900 0.82 CARM1 (0.68) CARM1
SCHEMBL4566594 0.82 CARM1 (0.67) CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008104077-A1 SMALL MOLECULE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASES (PRMTS) METHYLGENE INC. (CA) 2008-09-04 WO disclosed