Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.67 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13910130 | 0.92 | GSK3B (0.71) | GSK3B | |
| SCHEMBL14063476 | 0.91 | GSK3B (0.69) | GSK3B | |
| SCHEMBL13721556 | 0.89 | GSK3B (0.52) | GSK3B | |
| SCHEMBL13910485 | 0.84 | GSK3B (0.85) | GSK3B | |
| SCHEMBL13910329 | 0.83 | GSK3B (0.89) | GSK3B | |
| SCHEMBL13910833 | 0.83 | GSK3B (0.80) | GSK3B | |
| SCHEMBL13910470 | 0.82 | GSK3B (0.73) | GSK3B | |
| SCHEMBL13910846 | 0.82 | GSK3B (0.70) | GSK3BHIF1A | |
| SCHEMBL13910315 | 0.82 | GSK3B (0.82) | GSK3B | |
| SCHEMBL13910835 | 0.82 | GSK3B (0.82) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427615-B2 | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2008-09-23 | — | — | US | disclosed |
| US-7427615-B2 | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2008-09-23 | — | — | US | disclosed |